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Abstract #0440

Free breathing T2* mapping of the Liver using a compressed sensing reconstruction

Paul de Heer1, Oliver J Gurney-Champion1, Jurgen H. Runge1,2, Remy Klaassen3, Jasper Schoormans1, Bram F. Coolen4, Hanneke W.M. van Laarhoven3, Gustav J. Strijkers4, Jaap Stoker1, and Aart J. Nederveen1

1Radiology, AMC, Amsterdam, Netherlands, 2Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, 3Medical Oncology, AMC, Amsterdam, Netherlands, 4Biomedical Engineering & Physics, AMC, Amsterdam, Netherlands

Hemochromatosis (iron overload) occurs in a range of liver diseaes.(1,2) Iron content can be measured invasively with liver biopsy but is commonly replaced by non-invasive MR measurements, including T2* mapping. This is commonly done in a breath-hold to reduce the effects of respiratory motion. In this work we show that a stack of stars radial golden angle T2* mapping multi echo sequence during free breathing in combination with CS reconstruction facilitates high resolution imaging in the liver. This approach bears promise beyond liver imaging for visualizing smaller organs and pathologies, e.g. the pancreas and lymph nodes.

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