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Abstract #0499

Improved Localisation of DBS Electrodes using Pseudo-Positive Contrast from a Zero-Echo-Time Acquisition

Rolf F Schulte1, Jeffrey Ashe2, Sohan Ranjan3, Julia Prusik4, Julie Pilitsis4, Stanley Hayes5, Anne Menini1, Florian Wiesinger1, and Ileana Hancu2

1GE Global Research, Munich, Germany, 2GE Global Research, Niskayuna, NY, United States, 3GE Global Research, Bangalore, India, 4Albany Medical College, Albany, NY, United States, 5Alliance Healthcare Radiology, Nathan Littauer, Gloversville, NY, United States

The goal of this work is to reduce artefact extent and improve localisation of deep-brain stimulation (DBS) electrodes with MRI. A Zero Echo-Time (ZTE) sequence was used for data acquisition in a phantom and a patient; the minimal signal voids around electrodes, the ZTE’s natural proton-density weighting and low SAR/B1rms make it ideal for imaging implants. A pseudo-positive contrast image was first generated by inverting ZTE image intensity values, fitting and subtracting the background signal; a centre of mass calculation and singular value decomposition were then employed for electrode detection. Similar-sized artefacts as in CT images and improved precision over standard T1-weighted imaging were demonstrated.

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