Abstract #0510

Effective Connectivity Network of Emotion Regulation in Soldiers with Trauma

D Rangaprakash^1,2, Michael N Dretsch^3,4, Thomas A Daniel^5,6, Thomas S Denney^1,5,7, Jeffrey S Katz^1,5,7, and Gopikrishna Deshpande^1,5,7

¹AU MRI Research Center, Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, ²Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States, ³Human Dimension Division, HQ TRADOC, Fort Eustis, Fort Eustis, VA, United States, ⁴U.S. Army Aeromedical Research Laboratory, Fort Rucker, Fort Rucker, AL, United States, ⁵Department of Psychology, Auburn University, Auburn, AL, United States, ⁶Department of Psychology, Westfield State University, Westfield, MA, United States, ⁷Alabama Advanced Imaging Consortium, Auburn University and University of Alabama Birmingham, Birmingham, AL, United States

Conscious regulation of emotions is essential for sound functioning of an individual, while its disruption leads to several severe symptoms observed in psychiatric disorders like posttraumatic stress disorder (PTSD) and mild-traumatic brain injury (mTBI). While the brain regions activated in emotion regulation have been elucidated in prior works, an understanding of the underlying network has been elusive. Employing an emotion regulation task, we discovered the network of emotion regulation in healthy soldiers, and dysregulation in soldiers with comorbid PTSD/mTBI (N=59). Our work is significant given that we present, for the first time, the evidence for the network of emotion regulation/dysregulation.

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