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Abstract #0515

Robust 2D Nyquist Ghost Correction for Simultaneous Multislice (SMS) EPI Using Phase Error Correction SENSE and Virtual Coil SAKE

Mengye Lyu1,2, Markus Barth3, Victor B. Xie1,2,4, Yilong Liu1,2, Yanqiu Feng1,5, and Ed X. Wu1,2

1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, People's Republic of China, 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, People's Republic of China, 3Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, 4Toshiba Medical Systems (China), Beijing, People's Republic of China, 5School of Biomedical Engineering, Southern Medical University, Guangzhou, People's Republic of China

Nyquist ghost is problematic in SMS EPI because the ghost is slice-dependent and can interfere with slice separation process. The inconsistency between positive and negative echoes can be represented by 2D phase error maps. This study presents a new and robust SENSE-based method. It estimates both phase error maps and coil sensitivities from one plain EPI based calibration scan, and then uses these maps for ghost-free SMS EPI reconstruction. Further, to improve coil sensitivity estimation, virtual coil SAKE is incorporated to reduce the high order Nyquist ghost in the calibration scan.

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