Nyquist ghost is problematic in SMS EPI because the ghost is slice-dependent and can interfere with slice separation process. The inconsistency between positive and negative echoes can be represented by 2D phase error maps. This study presents a new and robust SENSE-based method. It estimates both phase error maps and coil sensitivities from one plain EPI based calibration scan, and then uses these maps for ghost-free SMS EPI reconstruction. Further, to improve coil sensitivity estimation, virtual coil SAKE is incorporated to reduce the high order Nyquist ghost in the calibration scan.