Abstract #0602

Variability and Reproducibility of Multicenter Human Diffusion Measurements with Track-density Imaging Analysis

Qiqi Tong¹, Ting Gong¹, Peipeng Liang², Tianyi Qian³, Xu Yan³, Yi Sun³, Chen Li¹, Qiuping Ding¹, Hongjian He¹, Kuncheng Li², and Jianhui Zhong¹

¹Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, People's Republic of China, ²Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China, ³MR Collaboration NE Asia, Siemens Healthcare, Shanghai, People's Republic of China

In a multicenter imaging study, it is vital to properly evaluate the variability of image quality among scanners. For diffusion imaging, estimations based on ADC and FA measurements with tensor models have previously been studied. However, such evaluation is not sufficient for studies with more diffusion directions like HARDI or DSI. This study uses track-density imaging to estimate the variability and reproducibility of multi-shell diffusion images from multicenter data acquired in the same subjects.

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