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Abstract #0602

Variability and Reproducibility of Multicenter Human Diffusion Measurements with Track-density Imaging Analysis

Qiqi Tong1, Ting Gong1, Peipeng Liang2, Tianyi Qian3, Xu Yan3, Yi Sun3, Chen Li1, Qiuping Ding1, Hongjian He1, Kuncheng Li2, and Jianhui Zhong1

1Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, People's Republic of China, 2Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China, 3MR Collaboration NE Asia, Siemens Healthcare, Shanghai, People's Republic of China

In a multicenter imaging study, it is vital to properly evaluate the variability of image quality among scanners. For diffusion imaging, estimations based on ADC and FA measurements with tensor models have previously been studied. However, such evaluation is not sufficient for studies with more diffusion directions like HARDI or DSI. This study uses track-density imaging to estimate the variability and reproducibility of multi-shell diffusion images from multicenter data acquired in the same subjects.

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