We validate axon diameter and density estimates using a novel biomimetic brain phantom that emulates the microstructural features of white matter, consisting of hollow textile axons (“taxons”) on the micron scale with distinct intra- and extra-axonal compartments and crossing regions. Diffusion data acquired over a range of gradient strengths, directions and diffusion times were fitted with the TractCaliber approach. Taxon volume fractions were accurately estimated, and the diameters were slightly overestimated in areas with less densely packed fibers. Such phantoms may be useful for testing microstructural models of the diffusion signal, and for scanner and protocol calibration.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords