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Abstract #0610

Diffusion tensor and restriction spectrum imaging reflect different aspects of neurodegeneration in Parkinson’s disease

Tuva Hope1, Per Selnes2, Irena Rektorová3, Zuzana Balážová3, Anders Dale4, Atle Bjørnerud1, and Tormod Fladby2

1Oslo University Hospital, Oslo, Norway, 2Akershus University Hospital, Lørenskog, Norway, 3Central European Institute of Technology, Brno, Czech Republic, 4University of California San Diego, La Jolla, CA, United States

Diffusion measures within the brain are assumed to be associated with neuronal and glial structure and integrity. In this study, we compare how diffusion tensor imaging (DTI) and restriction spectrum imaging (RSI) detect micro-structural changes within brain regions associated with motor function in Parkinson's Disease.

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