Abstract #0610

Diffusion tensor and restriction spectrum imaging reflect different aspects of neurodegeneration in Parkinson’s disease

Tuva Hope¹, Per Selnes², Irena Rektorová³, Zuzana Balážová³, Anders Dale⁴, Atle Bjørnerud¹, and Tormod Fladby²

¹Oslo University Hospital, Oslo, Norway, ²Akershus University Hospital, Lørenskog, Norway, ³Central European Institute of Technology, Brno, Czech Republic, ⁴University of California San Diego, La Jolla, CA, United States

Diffusion measures within the brain are assumed to be associated with neuronal and glial structure and integrity. In this study, we compare how diffusion tensor imaging (DTI) and restriction spectrum imaging (RSI) detect micro-structural changes within brain regions associated with motor function in Parkinson's Disease.

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