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Abstract #0627

MRI Detection of Extramural Venous Invasion in Rectal Cancer: Correlation with Histopathology Utilizing Elastin Stain

Kartik Jhaveri1, Hooman Hosseini-Nik, Seng Thipphavong, Naziheh Assarzadegan, Ravi Menezes, Erin Kennedy, and Richard Kirsch

1UHN, University of Toronto, Toronto, ON, Canada

Extramural venous invasion (EMVI) in Rectal cancer is an independent predictor of local and distant recurrence, nodal disease and overall survival. Accurate preoperative EMVI detection has implications for treatment decisions. Previously, MRI has been evaluated for this purpose previously against histopathology with Hematoxylin-Eosin(HE) staining. Recently histopathology with Elastin stain has been recommended for EMVI detection given its 2-3-fold increase in accuracy and improved prognostication compared to HE stain. The diagnostic performance of MRI for EMVI detection compared to elastin stain based histopathology is unknown and in this study, we present our results to address this issue.

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