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Abstract #0652

Simultaneous T2 Relaxometry and Morphometry of Cartilage and Meniscus with Double-Echo in Steady-State in Five Minutes

Akshay S Chaudhari1, Marianne S Black1, Bragi Sveinsson1, Garry E Gold1, and Brian A Hargreaves1

1Radiology, Stanford University, Stanford, CA, United States

Quantitative MRI parameters such as T2 relaxation times and morphometry are potential biomarkers for tracking spatial and temporal changes in musculoskeletal diseases and injuries. While cartilage has been widely studied, the short-T2 of meniscus makes it challenging to quantify in short scan times. In this study, we optimized the double-echo steady-state (DESS) pulse sequence to produce high-resolution and high signal-to-noise ratio images in five minutes. We compared the relaxometry and morphometry measures against established methods and found no significant differences. This suggests that a five-minute DESS scan could be used for simultaneous relaxometry and morphometry of the cartilage and meniscus.

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