Abstract #0681

A Calibrated Perfusion Phantom for Quality Assurance of Quantitative Arterial Spin Labelling.

Aaron Oliver-Taylor¹, Miguel Gonçalves¹, Thomas Hampshire¹, Bradley Davis¹, Pankaj Daga¹, Laura Evans¹, Alan Bainbridge², Claudia Wheeler-Kingshott³, Magdalena Sokolska², John Thornton⁴, Enrico De Vita⁴, and Xavier Golay^1,3

¹Gold Standard Phantoms Limited, London, United Kingdom, ²Medical Physics and Biomedical Engineering, UCLH NHS Trust, London, United Kingdom, ³Institute of Neurology, University College London, London, United Kingdom, ⁴Lysolm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom

Arterial Spin Labelling shows great promise for perfusion measurements, however its clinical adoption is precluded by the lack of a standardised phantom to validate such measurements. A perfusion phantom specially designed and built for optimal use with clinical ASL sequences is presented, alongside characterisation results. Measurements of perfusion rate and arterial transit time were made using a multi-TI FAIR PASL sequence. Results indicate the phantom has good stability, high SNR and exhibits perfusion rates and arterial transit times that are comparable with human physiology.

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