Brain tumor DSC-MRI studies can be confounded by T1 and T2* effects that occur when the contrast agent extravasates. Traditionally a combination of contrast agent pre-loading and leakage correction techniques are used to minimize T1 leakage effects, but currently there is no consensus on the most robust dosing scheme. Using a validated DSC-MRI digital reference object we characterize the influence of pre-load dosing schemes, acquisition pulse parameters, and leakage correction methods on CBV accuracy. Our goal is to leverage this computational approach to identify the optimal combination of parameters for brain tumor CBV mapping.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords