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Abstract #0746

Improving B1 Field Efficiency and Reducing noise for In Vivo 31P MRSI with Ultrahigh Dielectric Constant Material

Byeong-Yeul Lee1, Xiao-Hong Zhu1, Sebastian Rupprecht2, Michalel T. Lanagan3, Qing X. Yang2, and Wei Chen1

1Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota Medical School, Minneapolis, MN, United States, 2Center for NMR Research, Department of Radiology, The Pennsylvania State College of Medicine, Hershey, PA, United States, 33Department of Engineering Science and Mechanics, The Pennsylvania State College of Engineering, University Park, PA, United States

X-nuclei MRS for human application faces two challenges: high RF power requirement (thus, higher SAR) for achieving the same RF pulse flip angle due to a relatively lower gyromagnetic ratio, and limit of detection sensitivity (or SNR) even at high/ultrahigh field. In this work, we report that by incorporating ultra-high dielectric constant (uHDC) material into the RF head volume coil, huge RF transmit power reduction was observed in the regions near the uHDC pads for 31P MRSI at 7T. Concomitantly, the B1 efficiency for acquiring the spectra was increased about 100%. Strikingly, up to ~20% denoising effect was also observed with the uHDC material. Our results demonstrated that incorporating uHDC with RF coil can significantly boost SNR and reduce SAR in X-nuclei MRS applications; such improvements are beyond the gains obtainable at very high field strength magnet that has approached to its technologic limits.

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