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Abstract #0778

Assessing the effect of head-motion on tissue volume estimates

Daniel Gallichan1,2

1School of Engineering, Cardiff University, Cardiff, United Kingdom, 2EPFL- CIBM, Lausanne, Switzerland

We looked at data from 60 subjects undergoing 1mm resolution T1-weighted structural scans at 7T with 3D FatNavs allowing retrospective motion-correction. Motion parameters for 60 subjects were examined for general trends – and typical motion was dominated by translation in the z-direction and a small backwards rotation of the head. Quantitative estimates of tissue volumes were compared before and after motion-correction was applied, suggesting that total intracranial volume tends to be overestimated when the subject moves more – and that this is dominated by an overestimation of the CSF volume.

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