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Abstract #0781

Motion correction on a human PET/MR scanner: Clinical feasibility of a motion correction system in patients – an update report

Thomas Küstner1,2, Christian Würslin3, Martin Schwartz2,4, Hadi Fayad5, Thibaut Merlin5, Christopher Gilliam6, Thierry Blu6, Petros Martirosian4, Fritz Schick4, Bin Yang2, Holger Schmidt1, and Nina F Schwenzer1

1Department of Radiology, University of Tuebingen, Tuebingen, Germany, 2Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, 3University of Stanford, Palo Alto, CA, United States, 4Section on Experimental Radiology, University of Tuebingen, Tuebingen, Germany, 5LaTIM, INSERM, University of Bretagne, Brest, France, 6Department of Electronic Engineering, Chinese University of Hong Kong, Hong Kong, Hong Kong

The diagnostic accuracy of Positron-Emission-Tomography/Magnetic Resonance (PET/MR) is often reduced in regions affected by respiratory and cardiac motion. These motion-induced artifacts can be corrected by an MR-derived motion model (MM). Here, we improved the previously presented PET/MR motion correction system by two new sampling trajectories for the MR motion imaging and extend it by the usage of an additional Compressed Sensing reconstruction (BART), an optical-flow based registration (LAP) and the incorporation of motion correction into a listmode-based PET reconstruction (CASToR) which are all integrated into the Gadgetron-based reconstruction pipeline for a clinical feasible setup. In-vivo patient data substantiated the improvements.

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