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Abstract #0831

Using dynamic MRI to create moving boundary conditions for CFD: determining the causes of upper airway motion in sleep apnea

Alister Bates1,2, Andreas Schuh3, Brynne Williams2, Matthew Lanier2, Keith McConnell1, Wolfgang Loew2, Robert Fleck4, Jason Woods1,2, Charles Dumoulin2, and Raouf Amin1

1Division of Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, OH, United States, 2Imaging Reseach Center, Cincinnati Children's Hospital, Cincinnati, OH, United States, 3Department of Computing, Imperial College London, London, United Kingdom, 4Division of Radiology, Cincinnati Children's Hospital, Cincinnati, OH, United States

The upper airway consists of complex mobile structures such as the tongue, soft palate and larynx that make predicting surgical outcomes in obstructive sleep apnea difficult. Dynamic computational fluid simulations provide a method to assess the causes of airway deformation, but require information on the airway shape and motion. Combining MR imaging from three sequences provides this information in high spatiotemporal resolution. Simulations allow characterization of airway wall motion as either in the same or opposite direction as the force applied by the intraluminal airflow, which can be used to better understand the subject-specific mechanics of sleep apnea.

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