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Abstract #0836

Quantifying neuronal microstructure integrity with TE dependent Diffusion Imaging (TEdDI)

Jelle Veraart1, Els Fieremans1, and Dmitry S. Novikov1

1Center for Biomedical Imaging, New York University School of Medicine, New York, NY, United States

We resolve degeneracies in the estimation of parameters of white matter integrity by exploiting the observed echo time dependency of diffusion MRI signal in human brain white matter. Empirical results and statistical analyses reveal that adding compartment-specific T2 relaxation times to biophysical models of diffusion MRI improves the parameter estimation in terms of precision and accuracy.

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