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Abstract #0850

Simultaneous R2* and Quantitative Susceptibility Mapping of Trabecularized Yellow Bone Marrow: Initial Results in the Calcaneus

Maximilian Nikolaus Diefenbach1, Jakob Meineke2, Peter Foehr3, Stefan Ruschke1, Thomas Baum1, Jan S Kirschke4, Andreas Hock5, Hendrik Kooijman5, Ernst J Rummeny1, and Dimitrios C Karampinos1

1Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, 2Philips Research Laboratory, Hamburg, Germany, 3Department of Orthopedics and Sport Orthopedics, Technical University of Munich, Munich, Germany, 4Section of Neuroradiology, Technical University of Munich, Munich, Germany, 5Philips Healthcare, Hamburg, Germany

R2* mapping has been previously used to measure trabecular bone density by quantifying the magnetic field inhomogeneity effects induced by the susceptibility difference between trabecular bone and marrow. Quantitative susceptibility mapping (QSM) has been emerging in other body parts for measuring the field-independent magnetic susceptibility. Trabecular bone is in many locations embedded in yellow fatty marrow. Therefore, trabecular bone QSM requires to account for the presence of fat. The purpose of the present work is to develop a methodology for simultaneous R2* mapping and QSM of trabecularized yellow bone marrow and apply the technique in the calcaneus of healthy volunteers.

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