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Abstract #0938

Off-Resonance Correction for MR Fingerprinting Using Multiple Frequency Interpolation

Jason Ostenson1,2, Ryan K. Robison3, Nicholas R. Zwart3, and E. Brian Welch1,4,5

1Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, 2Program in Chemical and Physical Biology, Vanderbilt University, Nashville, TN, United States, 3Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, United States, 4Department of Radiology and Radiological Sciences, Vanderbilt University, 5Department of Biomedical Engineering, Vanderbilt University

While T1 and T2 parameter mapping using fast imaging with steady-state precession (FISP) magnetic resonance fingerprinting (MRF) has shown consistency with classic relaxometry techniques under static field (B0) inhomogeneity, the use of spiral k-space trajectories blurs parameter map boundaries in regions of high B0 variability. This work shows deblurring in phantom and in vivo relaxation maps generated using a published MRF sequence in conjunction with multi-frequency interpolation (MFI) acquired using undersampled and fully sampled spirals on a 3 Tesla human MR scanner.

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