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Abstract #0993

Asymmetries of the balanced SSFP profile allow to probe microstructure anisotropy at 9.4 Tesla

Philipp Ehses1,2, Mario Gilberto Báez-Yánez2,3, Michael Erb1, and Klaus Scheffler1,2

1Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany, 2Dept. of High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 3Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, Germany

The bSSFP signal profile exhibits tissue-dependent asymmetries that can be used as a novel contrast mechanism and have been hypothesized to relate to the tissue microenvironment. In this work, we investigate this effect at ultra high-field using phase-cycled bSSFP at an isotropic resolution of 1.2 mm. As in the original publication, we also observe strong asymmetries in white matter and a comparison to DTI data reveals that the largest asymmetries occur in white matter tracts oriented orthogonal to the main magnetic field.

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