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Abstract #1136

Measurement of Human Brain, Scalp, and Skull Motion in vivo using Magnetic Resonance Elastography and Triaxial Accelerometers

Andrew A Badachhape1, Ruth J Okamoto2, Curtis L Johnson3, and Philip V Bayly1,2

1Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States, 2Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO, United States, 3Biomedical Engineering, University of Delaware, Newark, DE, United States

Characterizing motion transmission from the skull to the brain and from skull to external soft tissue would provide valuable insight into traumatic brain injury mechanics and injury assessment by external sensors. In this study, we estimated rigid-body displacement components of brain and scalp using magnetic resonance elastography for comparison with skull motion estimated from three triaxial accelerometers. Comparison of the relative amplitudes and phases of harmonic motion in the skull, scalp, and brain of five human subjects indicated differences between each region. These measured amplitude and phase relationships can improve both simulations and experimental characterization of head biomechanics.

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