Emphysema is a chronic respiratory disease, which has become the fifth most common cause of death worldwide. Emphysema is characterized by alveolar wall destruction, leading to distal airspace enlargement and decreased elastic recoil. The altered structure and function of the lung is related to modified mechanical properties of pulmonary tissues, which are difficult to probe in vivo by standard techniques. Magnetic Resonance Elastography (MRE) allows to characterize the mechanical properties correlated with lung physiopathologies. Here, we implemented MRE lung imaging in vivo on emphysematous rat models.
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