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Abstract #1198

Echo-planar imaging with wave-CAIPI acquisition and reconstruction

Benedikt A Poser1, Berkin Bilgic2, Borjan A. Gagoski3,4, Kâmil Uludağ1, V Andrew Stenger5, Lawrence L Wald2,6,7, and Kawin Setsompop2,6

1Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States, 4Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children’s Hospital, Boston, MA, United States, 5Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, United States, 6Harvard Medical School, Boston, MA, United States, 7Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

wave-CAIPI allows for high undersampling factors and hence acquisition speed-up in anatomical imagines sequences including 3D GRE, 2D SMS-TSE and MP-RAGE (3D TFL). The coil array’s full 3D sensitivity encoding is exploited, resulting in negligible g-factor penalties even in highly accelerated scans. Echo-planar imaging (EPI) sequences, both 2D and 3D EPI with Cartesian blipped-CAIPI have recently brought tremendous speed-up to BOLD and diffusion imaging in the neurosciences. We here explore the potential of going beyond blipped-CAIPI EPI by incorporating sinusoidal z- and y- gradient wave perturbations into the EPI readout. Initial results are shown for 3D wave-CAIPI EPI at 7T.

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