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Abstract #1214

Nuclear susceptibility shift

Seung-Kyun Lee1,2, Jinil Park1,2, Jeongtaek Lee1,2, and Jang-Yeon Park1,2

1Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, 2Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science, Suwon, Korea, Republic of

We have observed in a clinical scanner that the center frequency of water MRI changed with the 1H spin flip angle. The amount of the change could be explained by the tip-angle dependent nuclear spin paramagnetic susceptibility, much the same way as the usual, tissue electronic para- and dia-magnetic susceptibility induces B0 shift in MRI. The observed shift, corresponding to nuclear susceptibility of +0.004 ppm in water, may affect the ultimate accuracy of MR-based tissue magnetic susceptibility measurements if not properly accounted for.

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