ASPIRES is a novel method for accelerated, high-resolution, large-bandwidth echo-planar spectroscopic imaging. It uses readout segmentation to decouple the echo spacing from the spatial resolution and gradient-system performance. Readout segmentation is combined with blipped phase encoding to accelerate scans by random undersampling along the readout-segment, phase-encoding and time directions. An elliptical acquisition window in the readout-phase encoding plane reduces scan time further. Distributed-multisensory compressed sensing reconstruction efficiently restores signal properties in both spatial and frequency domains. ASPIRES promises to enhance the diagnostic performance of MR spectroscopic imaging in clinical routine and improve the study of metabolites at high field strengths.
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