Readout-segmented EPI (RS-EPI) and interleaved-EPI (iEPI) are the two most widely used multishot EPI techniques for high resolution DWI. Many methods have been proposed to correct the motion-induced phase variations and rigid-motion in RS-EPI and iEPI. To compare the performance of motion correction in RS-EPI and iEPI, DWI and DTI simulations were designed. The correction methods we implemented for RS-EPI and iEPI take account of motion-induced phase variation, bulk motion and altered diffusion gradient orientation due to rotation. In our test, iEPI show less artifacts, however the b-matrix correction of RS-EPI is more straightforward with better accuracy.
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