Abstract #1324

RF pulse design by optimal control with physical constraints

Armin Rund^1,2, Christoph Stefan Aigner³, Karl Kunisch¹, and Rudolf Stollberger^2,3

¹Institute for Mathematics and Scientific Computing, University of Graz, Graz, Austria, ²BioTechMed Graz, Graz, Austria, ³Institute of Medical Engineering, Graz University of Technology, Graz, Austria

The design of customized RF pulse and slice selective gradient shapes gives rise to an optimal control problem for the Bloch equation with different inequality constraints. A state-of-the-art method of optimal control is designed especially for this problem class. The optimization model and method is applied to recent test examples. The results are validated on a 3T scanner with phantom and in vivo measurements.

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