Multiparametric MRI is the standard to evaluate suspected prostate cancer. T2-weighted and DWI are essential, while DCE is less crucial. We here demonstrate that simultaneous quantification of ADC, T2-relaxation and perfusion fraction f, which was calculated from non-IVIM low b-value data, is feasible in combination with 11C-acetate PET/MR imaging. ADC and T2-values differed significantly between healthy tissue and cancer, while f was more inconsistent. An important benefit of simultaneous acquisition is the lack of image mismatch between T2-maps and DWI. This enables more objective tumor grading, decreased inter-rater variability and using mathematical/statistical approaches or computer-aided detection to estimate cancer probability.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords