Abstract #1362

STEAM-CPMG: A method for localized Pulsed-Field-Gradient-Stimulated-Echo CPMG acquisitions

Ericky Caldas de Almeida Araujo^1,2,3 and Olivier Scheidegger^1,3,4

¹Institute of Myologie, La Pitié-Salpêtrière University Hospital, Paris, France, ²CEA/DRF/I2BM/MIRCen, Fontenay aux Roses, France, ³Institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, ⁴Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

The CPMG method has been long applied for multi-component T2 studies which have been shown to reveal the micro-anatomical compartmentation of water in biological tissue. A new method for localized CPMG acquisitions that makes use of the Stimulated Echo Acquisition Mode technique is presented. Besides offering localized T2-relaxation data within less than 10 s, the method is suited for performing Diffusion-Relaxation-Correlation-Spectroscopy studies. Such studies allow evaluating the translational diffusion of the different T2-compartments observed in vivo and shall offer new insights on diffusion and relaxation processes in biological tissues. The method has been validated in vitro.

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