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Abstract #1362

STEAM-CPMG: A method for localized Pulsed-Field-Gradient-Stimulated-Echo CPMG acquisitions

Ericky Caldas de Almeida Araujo1,2,3 and Olivier Scheidegger1,3,4

1Institute of Myologie, La Pitié-Salpêtrière University Hospital, Paris, France, 2CEA/DRF/I2BM/MIRCen, Fontenay aux Roses, France, 3Institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, 4Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

The CPMG method has been long applied for multi-component T2 studies which have been shown to reveal the micro-anatomical compartmentation of water in biological tissue. A new method for localized CPMG acquisitions that makes use of the Stimulated Echo Acquisition Mode technique is presented. Besides offering localized T2-relaxation data within less than 10 s, the method is suited for performing Diffusion-Relaxation-Correlation-Spectroscopy studies. Such studies allow evaluating the translational diffusion of the different T2-compartments observed in vivo and shall offer new insights on diffusion and relaxation processes in biological tissues. The method has been validated in vitro.

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