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Abstract #1373

Utilization of MR Elastography for selective boost to dominant intraprostatic lesions

Lumeng Cui1,2, Paul Babyn3, Francis Bui4, and Niranjan Venugopal1

1Medical Physics Department, Saskatoon Cancer Centre, Saskatchewan Cancer Agency, Saskatoon, SK, Canada, 2Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, 3Department of Medical Imaging, University of Saskatchewan and Saskatoon Health Region, Saskatoon, SK, Canada, 4Department of Electrical & Computer Engineering, University of Saskatchewan, Saskatoon, SK, Canada

MRE has the ability to distinguish between elastic properties of the tissue. Furthermore, it is maturing as a technique to differentiate normal and cancerous tissue. In this work we present a strategy to establish high quality MRE data, and present a method to incorporate this information into a radiation treatment planning framework. This new information is used to evaluate the efficacy of dose escalation to dominant intraprostatic lesions using a volumetric modulated arc therapy technique.

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