Abstract #1373

Utilization of MR Elastography for selective boost to dominant intraprostatic lesions

Lumeng Cui^1,2, Paul Babyn³, Francis Bui⁴, and Niranjan Venugopal¹

¹Medical Physics Department, Saskatoon Cancer Centre, Saskatchewan Cancer Agency, Saskatoon, SK, Canada, ²Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, ³Department of Medical Imaging, University of Saskatchewan and Saskatoon Health Region, Saskatoon, SK, Canada, ⁴Department of Electrical & Computer Engineering, University of Saskatchewan, Saskatoon, SK, Canada

MRE has the ability to distinguish between elastic properties of the tissue. Furthermore, it is maturing as a technique to differentiate normal and cancerous tissue. In this work we present a strategy to establish high quality MRE data, and present a method to incorporate this information into a radiation treatment planning framework. This new information is used to evaluate the efficacy of dose escalation to dominant intraprostatic lesions using a volumetric modulated arc therapy technique.

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