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Abstract #1402

Patch-based super-resolution for arterial spin labeling MRI

Cédric Meurée1,2,3,4,5, Pierre Maurel2,3,4,5, Elise Bannier2,3,4,5,6, and Christian Barillot2,3,4,5

1Siemens Healthineers, Saint-Denis, France, 2Univ Rennes 1, F - 35043, Rennes, France, 3INRIA, F - 35042, Rennes, France, 4INSERM, U746, F - 35042, Rennes, France, 5CNRS, U 6074, F - 35042, Rennes, France, 6CHU Rennes, F - 35033, Rennes, France

Partial volume effects (PVE) are an important limitation of arterial spin labeling (ASL) acquisitions, impacting the validity of quantitative cerebral blood flow (CBF) estimations. This abstract presents a super-resolution algorithm, which includes information of high resolution (HR) structural images to reconstruct HR CBF maps from low resolution ASL series, without increasing the acquisition time. Compared with nearest neighbor, trilinear and 3rd order spline interpolations, the proposed algorithm is found to generate a CBF image closer to the one obtained with a reference HR ASL acquisition. CBF calculations can therefore be improved by using this algorithm, which reduces the PVE.

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