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Abstract #1454

Validation of CSF based calibration for accurate and robust quantification of water content.

Zaheer Abbas1,2, Dominik Ridder1, Krzysztof Dzieciol1, and Nadim Jon Shah1,2

1Medical Imaging Physics, Institute of Neuroscience and Medicine, Juelich, Germany, 2Faculty of Medicine, RWTH Aachen, JARA, Aachen, Germany

Estimating tissue water content is challenging. Reliable quantification of the water content requires significant number of corrections and calibration to a reference. In this work, we proposed to use a region in cerebrospinal fluid for robust calibration; this is further validated in a cohort of healthy volunteers and compared to existing methods.

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