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Abstract #1471

Quantitative DCE-MRI Accuracy Evaluation Using Dynamic Physical vs. Digital Phantom: a Cross-Validation

Yuan Le1, Yuxiang Zhou2, Eric Stinson3, Stephen J. Riederer3, and Joel P. Felmlee3

1Radiology, Mayo Clinic Arizona, Scottsdale, AZ, United States, 2Radiology, Mayo Clinic Arizona, Phoenix, AZ, United States, 3Radiology-Diagnostic, Mayo Clinic, Rochester, MN, United States

To study the image accuracy of quantitative DCE-MRI a digital phantom and computer simulation were usually used. To validate the digital phantom method, we conducted a cross-validation study comparing the image accuracy estimation from simulation with that from a dynamic physical phantom with contrast infusion. Results showed that the estimated errors were usually higher with the physical phantom, likely due to the difference in reproducibility. Consistency was found in the measurement error comparison between imaging techniques when the temporal resolution was high.

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