Meeting Banner
Abstract #1486

Diffusion-weighted Echo Planar Spectroscopic Imaging in human brain at 3T

Manoj K Sarma1, Zohaib Iqbal1, Andres Saucedo1, Paul M Macey2, and M. Albert Thomas1

1Radiological Sciences, UCLA School of Medicine, Los Angeles, CA, United States, 2School of Nursing, UCLA School of Medicine, Los Angeles, CA, United States

There have been only few attempts to obtain maps of the diffusion properties of brain metabolites with diffusion weighted spectroscopic imaging. In this study we developed an echo planar based diffusion weighted spectroscopic imaging (DW-EPSI) method which uses a pairs of bipolar diffusion gradient to measure the apparent diffusion coefficient (ADC) of metabolites across an entire slice. The sequence was tested and validated on phantom and five healthy volunteers. The ADC values from DW-EPSI are in agreement with previous studies. The novel technique will enable a better understanding of the intracellular metabolism and water diffusivity correlates in pathologies.

This abstract and the presentation materials are available to members only; a login is required.

Join Here