Abstract #1501

A new ultrafast 3D gradient-echo-based imaging method: RASE-II

JaeKyun Ryu^1,2, WonBeom Jung^1,2, Sun Young Chae^1,3, Geun-Ho Im^4,5, Jung Hee Lee^1,3,4, Seong-gi Kim^1,2, and Jang-Yeon Park^1,2

¹Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon, Korea, Republic of, ²Department of Biomedical Engineering Sungkyunkwan University (SKKU), Suwon, Korea, Republic of, ³Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea, Republic of, ⁴Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea, Republic of, ⁵Department of Radiology, Samsung Medical Center, Sungkyunkwan University, Seoul, Korea, Republic of

One version of a new ultrafast gradient-echo-based 3D imaging technique using spatiotemporal encoding (RASE-II) is proposed which provides constant TE across all spins. RASE-II maintains most of appealing features of other spin-echo-based SPEN imaging methods such as no Nyquist ghosting and high tolerance to field inhomogeneities. RASE-II also has less sensitivity not only to SAR and B₁-inhomogeneity effects because of low flip angles, but also to T₂^* signal modulation due to constant TE. As a promising tool for fMRI, RASE-II shows significant improvement of tSNR over GE-EPI. Its performance is demonstrated by lemon and in-vivo rat brain imaging at 9.4T.

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