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Abstract #1501

A new ultrafast 3D gradient-echo-based imaging method: RASE-II

JaeKyun Ryu1,2, WonBeom Jung1,2, Sun Young Chae1,3, Geun-Ho Im4,5, Jung Hee Lee1,3,4, Seong-gi Kim1,2, and Jang-Yeon Park1,2

1Center for Neuroscience Imaging Research, Institute for Basic Science (IBS), Suwon, Korea, Republic of, 2Department of Biomedical Engineering Sungkyunkwan University (SKKU), Suwon, Korea, Republic of, 3Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea, Republic of, 4Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea, Republic of, 5Department of Radiology, Samsung Medical Center, Sungkyunkwan University, Seoul, Korea, Republic of

One version of a new ultrafast gradient-echo-based 3D imaging technique using spatiotemporal encoding (RASE-II) is proposed which provides constant TE across all spins. RASE-II maintains most of appealing features of other spin-echo-based SPEN imaging methods such as no Nyquist ghosting and high tolerance to field inhomogeneities. RASE-II also has less sensitivity not only to SAR and B1-inhomogeneity effects because of low flip angles, but also to T2* signal modulation due to constant TE. As a promising tool for fMRI, RASE-II shows significant improvement of tSNR over GE-EPI. Its performance is demonstrated by lemon and in-vivo rat brain imaging at 9.4T.

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