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Abstract #1503

Blood saturation modeling in multiband multislab Time-of-Flight brain MRI

Alexis Amadon1, Gaël Saïb1, Nicolas Boulant1, and Alexandre Vignaud1

1DRF / I2BM / NeuroSpin / UNIRS, CEA-Saclay, Gif-sur-Yvette, France

Multiband multislab Time-of-Flight angiography has recently been proposed for reduced acquisition time and improved sensitivity in the human brain at 3T and 7T. However, in these previous studies, blood saturation has not been taken into account as blood traverses several slabs acquired simultaneously. Here a simple modeling of blood magnetization history is provided to take this saturation into account, which appears essential to avoid strong losses of blood to background signal ratio. Slab-dependent multiband-added VUSE pulses are simulated to counteract these losses both at 3T and 7T, from which a methodology is derived to optimize multiband TOF sequence parameters.

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