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Abstract #1506

SNR Efficiency of Combined Bipolar Gradient Echoes: Theoretical Expressions and Experimental Verification

Jean-David Jutras1, Keith Wachowicz1,2, and Nicola De Zanche1,2

1Oncology, University of Alberta, Edmonton, AB, Canada, 2Medical Physics, Cross Cancer Institute, Edmonton, AB, Canada

Multi-echo bipolar pulse sequences are becoming increasingly popular in structural brain imaging applications that require high SNR efficiency and minimal geometrical distortions or water-fat shifts. However, various discrepant expressions for the SNR as a function of T2* and the sampling bandwidth were previously reported, making it unclear as to how multiple bipolar echoes should be combined to maximize SNR. In this study, we compare some traditional single-echo (low-bandwidth) FLASH and MPRAGE sequences with their multi-echo bipolar (high bandwidth) counterparts and validate the SNR theory via phantom measurements. Bipolar MPRAGE/FLASH yield SNR gains of ~1.3/1.6-fold, in good agreement with the theory.

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