Recently, more fMRI studies are aiming to assess the role of small anatomical regions of the brain in cognitive processes which requires sub-millimiter voxel resolution. At high resolution rigid body motion during the acquisition plays a significant role. The aim of this study is to assess the potential benefits of correcting for subject motion introduced distortions and image degradation prospectively in fMRI studies. This study demonstrates that prospective motion correction increases tSNR and therefore increases sensitivity. These results increment the potential applications of fMRI to unveil, more accurately, the role of smaller parts of the brain in different cognitive processes.
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