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Abstract #1631

Impact of prospective motion correction in 7T fMRI studies

Arturo Cardenas-Blanco1,2, David Berron2, Yi Chen2, Hendrik Mattern3, Renat Yakupov3, Alessandro Sciarra3, Oliver Speck1,3,4,5, and Emrah Düzel1,2

1DZNE, Magdeburg, Germany, 2Institute of cognitive neurology and dementia research (IKND), Magdeburg, Germany, 3Department of Biomedical Magnetic Resonance, Institute of Experimental Physics, Otto-von-Guericke-University, Magdeburg, Germany, 4Center for Behavioral Brain Sciences, Magdeburg, Germany, 5Leibniz Institute for Neurobiology, Magdeburg, Germany

Recently, more fMRI studies are aiming to assess the role of small anatomical regions of the brain in cognitive processes which requires sub-millimiter voxel resolution. At high resolution rigid body motion during the acquisition plays a significant role. The aim of this study is to assess the potential benefits of correcting for subject motion introduced distortions and image degradation prospectively in fMRI studies. This study demonstrates that prospective motion correction increases tSNR and therefore increases sensitivity. These results increment the potential applications of fMRI to unveil, more accurately, the role of smaller parts of the brain in different cognitive processes.

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