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Abstract #1808

Application of Weighted Diffusion Subtraction (WDS) to Synovial Sarcomas: Possibility of Visualising Tumor Cellularity

Manabu Arai1, Shigeo Okuda2, Sota Oguro2, Kuniaki Ohori2, and Koichi Oshio2

1Department of Radiology, Nippon Kokan Hospital, Kawasaki, Japan, 2Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo, Japan

DWI and ADC values are widely used for tissue characterization. However, the relationship between the ADC values and the histological findings is still controversial. Weighted diffusion subtraction (WDS) was originally developed to eliminate T2 shine-through ambiguity in diffusion MRI evaluations. In this study, we applied WDS technique to diffusion weighted images of synovial sarcomas to evaluate the complex and heterogeneous tissue. Correspondence was found between WDS and histological findings on visual inspection. WDS seems to be a valuable visualization tool.

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