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Abstract #1825

Effect of hyperglycemia on deep nucleus microstructure and iron deposition in people with type 2 diabetes: a DKI and SWI study

Junyi Dong1, Chengcheng Zheng1, Qingwei Song1, Qiang Wei1, Weiwei Wang1, Yanwei Miao1, and Bing Wu2

1Department of Radiology,First Affiliated Hospital of Dalian Medical University, Dalian 116011, People's Republic of China, 2GE healthcare China, Beijing

In this paper,the experimental group and the control group were respectively used as the people with type 2 diabetes and the health people ,the effect of high blood glucose on the microstructure and iron deposition in patients with type 2 diabetes mellitus was studied used DKI and SWI study,and it is concluded that the high blood glucose level may have certain damage to the microstructure of the deep core.Furthermore,iron deposition may exacerbate the damage of microstructure.In conclusion,DKI and SWI study can evaluate secondary brain microstructure changes from hyperglycemia in T2DM patients.

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