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Abstract #1829

Effect of gadolinium contrast agent on IVIM derived parameters of abdominal organs

Yukun Chen1, Chao Ma1, Aiguo Jin1, Li Wang1, Minjie Wang1, Luguang Chen1, Caixia Fu2, Xu Yan2, and Jianping Lu1

1Radiology, Changhai Hospital of Shanghai, Shanghai, People's Republic of China, 2MR Collaboration NE Asia, Siemens Healthcare, Shanghai, People's Republic of China

This study investigated potential effects of gadolinium contrast agent on the IVIM derived parameters such as Dfast (blood microcirculation), Dslow (pure extravascular water diffusion), f (perfusion fraction) and the commonly used DWI-derived ADC of abdominal organs. The result shows that gadolinium administration does not make statistically significant differences in Dslow, Dfast, f or ADC of the liver, spleen, or pancreas. In the kidney, however, ADC values are significantly lower with post-contrast than pre-contrast.

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