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Abstract #1946

Evaluation of dual-echo EPI for in-vivo current mapping in individual subjects during transcranial Direct Current Stimulation

Mayank S Jog1, Lirong Yan2, Kay Jann2, Lucas Parra3, Marom Bikson3, and Danny JJ Wang2

1Biomedical Engineering, University of California Los Angeles, Los Angeles, CA, United States, 2University of Southern California, CA, United States, 3Biomedical Engineering, City College of New York, NY, United States

Transcranial Direct Current Stimulation (tDCS) is a neuromodulation technique that uses milliampere currents to modulate cortical excitability. Although tDCS has been shown to treat clinical symptoms and improve cognition, the distribution of tDCS currents in the brain remains unknown. Here we show a MRI technique that measures a component of the magnetic field induced by tDCS currents in-vivo. Experimental data acquired using this technique is compared to model-based simulations. Our results demonstrate that mapping the tDCS current-induced magnetic fields in individual subjects is feasible; opening an avenue to map electric currents directly and track target engagement in individual subjects.

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