Abstract #1962

The challenge of phase offset correction for quantitative susceptibility mapping at ultra-high field

Steffen Bollmann¹, Simon Robinson², Kieran O'Brien^1,3, Viktor Vegh ¹, Andrew Janke¹, Lars Marstaller⁴, David Reutens¹, and Markus Barth¹

¹Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, ²High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, ³Siemens Healthcare Pty Ltd, Brisbane, Australia, ⁴Cardiff University, School of Psychology, Cardiff, United Kingdom

One challenge in quantitative susceptibility mapping (QSM) at ultra-high field (> 3 T) is the combination of phase data from phased array receive coils. We assessed the performance of COMPOSER (COMbining Phase data using a Short Echo-time Reference scan) with separate reference scans and with an intrinsic reference scan, as well as a reference-free single-channel method. Our results show that reference scans can bias QSM results at ultra-high field. We conclude that ultra-short echo-time reference scans reduce quantitation bias and remove the transmit field phase when using COMPOSER to combine phase data at ultra-high field.

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