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Abstract #1962

The challenge of phase offset correction for quantitative susceptibility mapping at ultra-high field

Steffen Bollmann1, Simon Robinson2, Kieran O'Brien1,3, Viktor Vegh 1, Andrew Janke1, Lars Marstaller4, David Reutens1, and Markus Barth1

1Centre for Advanced Imaging, University of Queensland, Brisbane, Australia, 2High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria, 3Siemens Healthcare Pty Ltd, Brisbane, Australia, 4Cardiff University, School of Psychology, Cardiff, United Kingdom

One challenge in quantitative susceptibility mapping (QSM) at ultra-high field (> 3 T) is the combination of phase data from phased array receive coils. We assessed the performance of COMPOSER (COMbining Phase data using a Short Echo-time Reference scan) with separate reference scans and with an intrinsic reference scan, as well as a reference-free single-channel method. Our results show that reference scans can bias QSM results at ultra-high field. We conclude that ultra-short echo-time reference scans reduce quantitation bias and remove the transmit field phase when using COMPOSER to combine phase data at ultra-high field.

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