Abstract #2010

HCC detection in pre-transplant patients: A comparative retrospective study between multiphasic CT, gadoxetic acid-enhanced MRI and extracellular gadolinium based contrast-enhanced MRI

Sahar Semaan¹, Christopher Song¹, Sara Lewis¹, Manjil Chatterji¹, M. Isabel Fiel², Cecilia Besa³, and Bachir Taouli³

¹Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

In this study, we present preliminary data comparing the diagnostic performance of multiphasic contrast-enhanced CT with contrast enhanced MRI using a liver specific gadolinium based contrast agent (GBCA), gadoxetic acid (Gd-EOB-DTPA) and extracellular (EC) GBCAs, using explant pathologic data as the reference. We also assessed the added value of delayed hepatobiliary phase (HBP) imaging and DWI in HCC detection. Our data suggests that CT and MRI have similar overall sensitivities for HCC detection and that the addition of DWI and HBP improved HCC detection when using Gd-EOB-DTPA.

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