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Abstract #2014

Gadoxetic acid disodium-enhanced magnetic resonance imaging for staging of liver fibrosis: a meta-analysis

Yuelang Zhang1, Xiang Li2, Haitian Liu1, Chenxia Li2, and Jian Yang 2

1The First Hospital of Medical School, Xi’an Jiaotong University, Xi'an, People's Republic of China, 2The First Hospital of Medical School, Xi’an Jiaoto, Xi'an, People's Republic of China

To collect and summarize parameters used by gadoxetic acid-enhanced MR imaging (GD-EOB-DTPA-enhanced MRI) for staging of liver fibrosis (LF) and evaluate diagnostic performance. A systematic literature search was performed in PubMed, Web of science, Embase and Medline database. Studies used frequently-used parameter were included. Pooled weighted mean difference (WMD) was applied to determine the clinical significance. Pooled sensitivity, specificity, and summary receiver operating characteristics (SROC) curve were calculated to evaluate diagnostic performance. Finally, 5 studies were included, and contrast enhancement index (CEI) was the most frequently-used parameter, which was considered to be an efficient biomarker in the staging of LF.

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