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Abstract #2025

Pancreatic changes in patients with liver cirrhosis and diabetes: a 3-T MRI evaluation

Tomohiro Sato1, Katsuyoshi Ito1, Tsutomu Tamada 1, Akira Yamamoto1, and Akihiko Kanki1

1Radiology, Kawasaki Medical School, Kurashiki city, Japan

The liver plays a pivotal role in glucose metabolism, so 60-80% of patients with cirrhosis experience impaired glucose tolerance and hyperinsulinemia, and 10-50% develop diabetes. This study was intended to clarify the extent to which pancreatic MRI findings are affected by the presence of diabetes mellitus in patients with liver cirrhosis. On 3-T MRI, size of the pancreas was significantly increased, the grade of pancreatic lobulation was significantly reduced, and pancreatic SIRs on T2WI with fat suppression were significantly increased in cirrhotic patients complicated with diabetes as compared to cirrhotic patients without diabetes.

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