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Abstract #2057

Quantitative MRI parameters for adipose tissue characterization in obese patients

Nikita Garnov1,2, Stefanie Lehmann2, Ulf Retschlag2, Nicolas Linder1,2, Alexander Schaudinn1,2, Arne Dietrich2,3, Andreas Oberbach2, Thomas Kahn1, and Harald Busse1

1Diagnostic and Interventional Radiology, Leipzig University Hospital, Leipzig, Germany, 2Integrated Research and Treatment Center (IFB) AdiposityDiseases, Leipzig University Medical Center, Leipzig, Germany, 3Department of Visceral, Transplantation, Thoracic and Vascular Surgery, Division of Bariatric Surgery, Leipzig University Hospital, Leipzig, Germany

In obesity research and clinical practice, disease progress or response to therapy is typically evaluated by the reduction of body weight, adipose tissue (AT) volume or comorbidity remission rates. However, little is currently known about therapy-induced changes in subcutaneous and visceral AT composition and how to quantify them. Lean control subjects had recently been shown to have significantly higher T1 relaxation times in both SAT (301 ms) and VAT (360 ms) than severely obese patients (275 and 294 ms, respectively). Aims of this study were to characterize AT by quantitative MRI and evaluate the intra-individual changes at two time points.

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