A histogram analysis approach has been shown to be a premising tool in discriminating malignant and benign SPNs in terms of their heterogeneity. The purpose of our study was thus to primarily assess the diagnostic performance of DCE-MRI for stratifying the malignant and benign using histogram analysis. The results showed that the mean value of Ktrans and Kep, Kurtosis and skewness assessments from Ve of DCE-MRI histograms may be useful for differentiating malignant from benign SPNs.
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