Prostate Cancer: Differentiation of Transition Zone Cancer from Benign Prostatic Hyperplasia by Using Diffusion Kurtosis imaging, Intravoxel Incoherent motion and ultra-high b-value apparent diffusion coefficient techniques

To evaluate the value of the (kurtosis, perfusion and diffusion) parameters in the differentiation of TZ cancer from benign GH.30 patients underwent preoperative 3-T magnetic resonance (MR) imaging. Each parameter in TZ carcinomas and GH were compared using Student's t test, receiver operating characteristics (ROC) analysis. All parameters except for D* in TZ carcinoma and GH were significantly different, and showed the same sensitivity for differentiating TZ carcinoma from GH (92.3%), and K and ADCs with equal specificity (96.7%).The monoexponential ultra-high b value ADC calculation is more practical to discriminate TZ carcinoma from GH.