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Abstract #2079

Prostate Cancer: Differentiation of Transition Zone Cancer from Benign Prostatic Hyperplasia by Using Diffusion Kurtosis imaging, Intravoxel Incoherent motion and ultra-high b-value apparent diffusion coefficient techniques

Yan Zhong1, Lu Ma2, Yanguang Shen, Yingwei Wang3, Jingjing Pan, Haiyi Wang, and Huiyi Ye

1Chinese PLA General Hospital, Beijing, People's Republic of China, 2Chinese PLA General Hospital, People's Republic of China, 3Chinese PLA General Hospital

To evaluate the value of the (kurtosis, perfusion and diffusion) parameters in the differentiation of TZ cancer from benign GH.30 patients underwent preoperative 3-T magnetic resonance (MR) imaging. Each parameter in TZ carcinomas and GH were compared using Student's t test, receiver operating characteristics (ROC) analysis. All parameters except for D* in TZ carcinoma and GH were significantly different, and showed the same sensitivity for differentiating TZ carcinoma from GH (92.3%), and K and ADCs with equal specificity (96.7%).The monoexponential ultra-high b value ADC calculation is more practical to discriminate TZ carcinoma from GH.

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