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Abstract #2082

The Histogram analysis of quantitative  Dynamic enhanced and Diffusion-weighted Intravoxel Incoherent Motion MRI for  pathologic Gleason grading of prostate cancer

Ru wen1, Junkang Shen2, Wenlu Zhao3, Peng Cao4, and Jiangfen Wu4

1Department of imaging, The second affiliated hospital of Soochow university, Soochow, People's Republic of China, 2The second affilicated hospital of Soochow university, soochow, People's Republic of China, 3The second affilicated hospital of Soochow university, People's Republic of China, 4GE healthcare China

There are different treatments for low-risk and high-risk prostate cancer patients in clinical, NCCN guidelines recommend proactive monitoring management as the preferred treatment for patients with low risk PCa(GS ≤6 ),and active measures for intermediate/high-risk patients. Our research found that both DCE and IVIM quantitative parameters Histogram analysis results can successfully distinguish LG from HG PCa ,and their diagnostic performance was not statistically significant. Considering the method we used to acquire quantitative parameters of DCE-MRI , IVIM may provide us a new way for those who cannot bear the invasive intravenous injection of contrast agent .

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