3D T2-weighted imaging (T2WI) of the prostate for prostate cancer (PCa) is often hampered by motion artifacts and signal starvation. However, incorporating reduced phase field of view capability using outer volume suppression (OVS) into 3D fast spin echo (FSE) can overcome these obstacles. In the prostatic transition zone (TZ), superior contrast and diminished blur were found over standard 2D FSE, with preserved SNR and anatomic detail. Diagnostic confidence was greater with 3D, whether used alone or in combination with 2D. Furthermore, less equivocal diagnoses resulted with the combination of 2D and 3D.